An English and Scottish surname, Middleton comes from the Old English terms ‘midel’ and ‘tun’ which mean a middle enclosure. The spelling variations for Middleton include Midleton, Myddleton, Myddelton and Middelton. In England the earliest Middleton families lived in Westmorland. Over the centuries they spread to Yorkshire, Durham, Lancashire, Norfolk, Derbyshire, Staffordshire and Warwickshire. There are also many in the city of London. In Scotland the Middleton surname is across the country. Most populated with the Middleton name is in Lanarkshire, Midlothian, Angus and Aberdeenshire. Within the United States the Middleton name originated in South Carolina, Kentucky, Georgia, New York, Pennsylvania, Texas and Virginia. Famous: Charles B. Middleton (actor), Kate Middleton (wife of England’s Prince William, married in 2011), Malcolm Middleton (musician from Scotland), Stanley Middleton (novelist from England), Joshua Middleton (comic book artist), Ian Middleton (novelist from New Zealand), George Middleton (playwright) and Darryl Middleton (professional basketball player).